Prototype of running clinical trials in an untrustworthy environment using blockchain

【Author】 Wong, Daniel R.; Bhattacharya, Sanchita; Butte, Atul J.

【Source】NATURE COMMUNICATIONS

【影响因子】17.694

【Abstract】Monitoring and ensuring the integrity of data within the clinical trial process is currently not always feasible with the current research system. We propose a blockchain-based system to make data collected in the clinical trial process immutable, traceable, and potentially more trustworthy. We use raw data from a real completed clinical trial, simulate the trial onto a proof of concept web portal service, and test its resilience to data tampering. We also assess its prospects to provide a traceable and useful audit trail of trial data for regulators, and a flexible service for all members within the clinical trials network. We also improve the way adverse events are currently reported. In conclusion, we advocate that this service could offer an improvement in clinical trial data management, and could bolster trust in the clinical research process and the ease at which regulators can oversee trials.

【Keywords】

【发表时间】2019 22-Feb

【收录时间】2022-01-02

【文献类型】理论模型

【主题类别】

区块链应用-实体经济-医疗领域