A Robust and Secure Drug Delivery With Single Transmitter and Dual Symmetrical Receivers in an Internet of Bio-Nano Things

【Author】 Bulasara, Phani Krishna; Sahoo, Somya Ranjan

【Source】IEEE INTERNET OF THINGS JOURNAL

【影响因子】10.238

【Abstract】Bio-nanomachines are designed for targeted drug delivery in the human body. Sometimes the drug is not distributed properly to the intended receiver due to the biochemical reactions and the possible bindings of drug molecules. The blockchain analogy for Bio-Nano has paved new ways for secure drug delivery. The drug molecule is protected with the help of protein cryptography and genetic signature. A protein membrane attached to the drug molecule acts as an encryption key and will be decrypted after matching with the Receiver's unique composition. But, in cellular biology, the protein membrane structures exhibit symmetries. So there is a high chance that the unintended tissues/organs might receive the drug. Hence, the required dosage of the drug will not reach the intended receiver. In our proposal, we are dealing with the appropriate and secure drug delivery for the symmetrical Receivers. A Control Unit monitors the statistics of a Transmitter nanomachine and two Receiver nanomachines to ensure appropriate drug dosage and delivery. We evaluated the Interarrival Time of molecules in a Poisson process following exponential distribution and the Probability of Successful Transmission of molecules. We have also analyzed the possibilities of the malfunctioning of nanomachines. The good working condition of nanomachines improved both the Probability Density Function of the Interarrival Times and the Probability of Successful Transmissions. In our work, we stick to the maximum number of retransmissions as only 1 and achieved a high Probability of Successful Transmissions.

【Keywords】Drugs; Nanobioscience; Receivers; Molecular communication; Transmitters; Targeted drug delivery; Nanoscale devices; Bio-nano things; capture probability; drug delivery; interarrival time; molecular communication; nanomachine; security; successful transmission

【发表时间】2024 JUL 15

【收录时间】2024-07-29

【文献类型】

【主题类别】

--